The THEW project celebrates the new year 2010 and its first anniversary
The THEW team wishes you a happy and successful New Year 2010. The THEW was openned the 15th of March 2009, and we would like to share with you our achievements for year 2009 while celebrating our first year anniversary. Amongst the important steps, one would emphasize the increased number of both for-profit and non-for-profit organizations that have joined our initiative and help us develop further the project. Importantly, the NHLBI became part of the project and has allocated significant funds to our initiative. Today, the THEW is fully functional with more than 500GB of continuous ECG recordings available from healthy individuals and cardiac patients. Data from drug safety studies (thorough QT studies), clinical studies (coronary artery disease patients, acute myocardial infarction patients, and healthy individuals), as well as patients with arrhythmias (tdps and atrial fibrillation recordings) are available to our members. The current list of dataset available in the warehouse is growing rapidely and we are updating the list of studies periodically .. More....
In June, we started the LinkedIn group for the Center for Quantitative Electrocardiography and Cardiac Safety (the organization hosting the THEW). More than 245 professionals have already joined. They received weekly updates about our activities (new members, working group and new database release). You can freely join this group.
To learn more about the tool to access the data from the warehouse, you can request for a demo. version of the THEW Client Application which provides access to a database containing a couple of Holter ECGs. Today, 50 organizations have downloaded the demo version of the THEW Client application.
The Executive Committee (EC) of the Telemetric and Holter ECG Warehouse (THEW) has been formed during the second quarter 2008, the seven individuals in the EC are from the Center for Drug Evaluation and Research, the Commissioner Office of the Food and Drug Administration (FDA) and the University of Rochester Medical Center. Read more about our group.
Keep informed about our activities by joining our LinkedIn group. More than 245 professionals have already registered.[12/16/2009]: The Director of the THEW interviewed by Technology Review published by the MIT: here.
[11/11/2009]: New Research Center to Focus on Cardiac Safety and Innovation in Pharmaceutical Industry Today: here.
[6/11/2009]: University of of Rochester and FDA Partner for ECG Database, Drug Discovery & Development Magazine. More info here
[5/6/2009] FDA website Existing Partnerships FDA’s Public-Private Partnership Program: THEW
[03/28/2009] Public and Private part- nership to help determine Clinical Biomarker Utility in Applied Clinical Trials online.com.>here
[1/13/2010] Members: The Oxford University Computing Laboratory is the first new member for year 2010. At the heart of computing and related interdisciplinary activity at Oxford, this centre focuses on research in computer science, numerical analysis, computational biology, quantum computation, computational linguistics, and information systems. The Computational Biology Group also plays a key role in interdisciplinary initiatives across the University, including the EU FP7 projects euHeart and PreDiCT.
[11/16/2009] Technology: The THEW announces the release of its HL7 XML extraction tool. The THEW client application allows for ECG to be exported in HL7 XML ECGs, an ECG format broadly used in drug safety trials.
[05/27/2008]: "THEW Beyond QT working Group" releases an ECG marker submission form designed in collaboration with the FDA.
| Healthy | E-HOL-03-201-003 |
| Coronary | E-HOL-03-271-002 |
| Acute MI | E-HOL-03-160-001 |
| TQT #1 | E-HOL-03-175-005 |
| TQT #2 | E-HOL-12-140-008 |
| TdPs | E-OTH-12-006-009 |
| History of TdPs | E-OTH-12-068-010 |
| Atrial Fibrillation | E-OTH-12-073-011 |
NHLBI Support[12/13/2009]:The University of Rochester and the NHLBI enabled the creation of a "Center for Quantitative Electrocardiography and Cardiac Safety" (CES). Read more...
Agreement[05/27/2008] FDA: Dr. J. Woodcock (Director, CDER-FDA) and Dr. Norman Stockbridge (Director for the Division of Cardiovascular and Renal Products, CDER-FDA) signed a Letter of Agreement officially starting the partnership between the FDA and University of Rochester for the THEW initiative. More...