New Members

[03/12/2014], University Medicine Berlin, Bonn, Germany, The Charite is one of the largest university hospitals in Europe. Here, 3700 doctors and scientists heal, do research and teach at the top international level. More than half of the German Nobel Prize winners in medicine and physiology come from the Charite, among them Emil von Behring, Robert Koch and Paul Ehrlich.

[01/23/2014], BioSign GmbH, Ottenhofen, Germany, Developing innovative measurement and therapy systems for professionals and end-users in the subject area vegetative (autonomic) nervous system. BioSign is responding to the growing medical recognition that disturbances in the autonomic nervous system and disturbances in the interplay of the various organs are involved with the autonomic nervous system.

[11/14/2013], University of Rochester, Computer and Electrical Engineering, Rochester, NY, USA. This department has multiple programs related to energy, to health and medicine, to the connected world, and to music. Specific research programs span a wide range, including medical imaging, image processing, genomics, audio and music signal processing, among others.

[10/31/2013], RIT, Microsystem Engineering, Rochester, USA The multidisciplinary program builds on the fundamentals of traditional engineering and science including the manipulation of electrical, photonic, optical, mechanical, chemical, and biological functionality to process, sense, and interface with the world at a nanometer scale.

[09/10/2013], Medtronic, Inc., Mounds View, USA Medtronic develops and manufactures innovative medical device technology and therapies to treat chronic disease worldwide.

[06/11/2013], RIT, Department of Biomedical Engineering, Rochester, USA The RIT mission is to provide technology-based educational programs for personal and professional development. We rigorously pursue new and emerging career areas. We develop and deliver curricula and advance scholarship relevant to emerging technologies and social conditions. Our community is committed to diversity and student centeredness and is distinguished by our innovative and collaborative spirit.

[05/02/2013], Masonic Medical Research Laboratory, Utica, NY, USA The Masonic Medical Research Laboratory is a not-for-profit institute dedicated to improving the health and quality of life for all. The Laboratory primary mission is to conduct high quality basic and clinical research aimed at generating knowledge and information necessary for development of the medical cures and treatments of tomorrow.

[04/22/2013], Universitat Politecnica de Catalunya (Barcelona-Tech), Barcelona, Spain. The Universitat Politecnica de Catalunya (UPC): BarcelonaTech is a public institution dedicated to higher education and research, specialised in the fields of engineering, architecture and science. With a focus on intellectual rigor, critical thinking, a transversal approach to knowledge, educational innovation and entrepreneurship, the UPC produces competent professionals with the skills they need to tackle present and future challenges.

[03/20/2013], Teschnische Universitat(TU), Dresden, Germany. The TU Dresden is one of eleven German universities that were identified as an Excellence University. TUD has about 36.500 students and almost 5319 employees, 507 professors among them, and, thus, is the largest university in Saxony.

[02/08/2013], Baskir State Pedagogical University (BSPU), Ufa City, Russia M. Akmullah BSPU is a large scientific, educational, cultural and social center of the Republic of Bashkortostan. It includes the Institute of Pedagogics, the Institute of Professional Education and Information Technologies, the Institute of Historical and Legal Education, the Institute of Philological Education and Cross-Cultural Communication and 7 departments with about 12 000 students.

[02/01/2013], Chung-Yuan Christian University, Taiwan, China Chung Yuan Christian University is founded on the spirit of Christian love for the world. With faith, hope, and love, we endeavor to promote higher education for the benefit of the Chinese people, aiming at the pursuit and advancement of genuine knowledge in order to maintain our cultural heritage and, thus, to serve humankind.

[12/11/2012], Cardio-QT Ltd., Glasgow,, United Kingdom Headed by Royal College Accredited Cardiologist and Bioengineer supported by PhD Scientists, Cardio-QT Ltd is an award winning, highly innovative Core Cardiac Analysis Laboratory offering an array of sophisticated validated techniques to solve all analytical research problems.

[10/21/2012], National Polytechnic Institute of Mexico, Mexico City,, Mexico The Institute is the State secular free education institution, guide of public technological education in Mexico. A leader in the generation, application, dissemination and transfer of scientific and technological knowledge.

[09/24/2012], Massachusetts General Hospital, Harvard Medical School , Charlestown, MA,, USA Mass General has long been a leader in successfully bridging innovative science with state-of-the-art clinical medicine. With an annual research budget of nearly $764 million, Mass General conducts the largest hospital-based research program in the United States - a program that spans more than 20 clinical departments and centers across the hospital. This funding drives discoveries and breakthroughs in basic and clinical research, which translate into new and better treatments that transform medical practice and patient care.

[05/24/2012], College of Veterinary Medicine, Cornell University, Ithaca, NY,, USA The mission of the Department of Biomedical Sciences is to educate and inform the veterinary and human biomedical communities through our diverse research and clinical service excellence as well as through our commitment to undergraduate, graduate, and veterinary teaching.

[05/02/2012], The Victor Chang Cardiac Research Institute (VCCRI), Sydney, Australia The VCCRI is committed to excellence in research into heart disease and cardiovascular biology, cardiovascular research training, and facilitating the rapid application of research discoveries to patient care.

[02/09/2012], Samsung Electronics Co., Future IT Research Center, SAIT , Gyeonggi,, Korea SAIT provides a full spectrum of support so its researchers can focus on creative research, seek the convergence of heterogeneous technologies and take up new challenges. Meanwhile, SAIT also actively engages in "open innovation" to jointly create future value with other research institutions through collaboration.

[01/26/2012], FDA-CDRH: Center for Devices and Radiological Health, Silver Spring, MD, USA FDA Center for Devices and Radiological Health (CDRH) is responsible for regulating firms who manufacture, repackage, relabel, and/or import medical devices sold in the United States. In addition, CDRH regulates radiation-emitting electronic products (medical and non-medical) such as lasers, x-ray systems, ultrasound equipment, microwave ovens and color televisions.

[01/10/2012], Department of Physiological Nursing, University of California, San Francisco, CA, , USA The Mission of the Department of Physiological Nursing prevention of UCSF is to study the prevention, measurement, and treatment of physiological and biobehavioral responses to health, illness/disease and aging. Psycho-physiological interrelationships and interventions also are studied. Research spans all phases of the health/illness trajectory including people who are healthy, critically ill, living with a chronic illness, and those at the end of life.

[01/03/2012], University of Bologna (HST-ICIR) , Bologna,, Italy The University of Bologna was probably the first University in the western world. Its history is one of great thinkers in science and the humanities, making it an indispensable point of reference in the panorama of European culture. Bologna has thus been called upon to forge relationships with institutions in the most advanced countries to modernise and expand its activity. Among the many challenges which it has met with success, Bologna committed itself to the European dimension which has now led to adoption of the new university system.

Press Center

[09/23/2010]: AstraZeneca joins the THEW to further cardiac safety inThe Medical News: here.

[12/16/2009]: The Director of the THEW interviewed by Technology Review published by the MIT: here.

[11/11/2009]: New Research Center to Focus on Cardiac Safety and Innovation in Pharmaceutical Industry Today: here.

[6/11/2009]: University of of Rochester and FDA Partner for ECG Database, Drug Discovery & Development Magazine. More info here

[5/6/2009] FDA website Existing Partnerships FDAs Public-Private Partnership Program: THEW

[03/28/2009] Public and Private part- nership to help determine Clinical Biomarker Utility in Applied Clinical Trials online.com.>here

Library Publications
Below is the list of publications refering to the THEW initiative or describing research works based on the data from our repository. Please click on a Collapsible Panel below to open or close it. The left colum provides the link to the manuscript or to its summary.
2014 - Manuscripts

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2014
4 publications
pdfKocabas O, Soyata T, Couderc JP, Aktas M, Xia J, and Huang M., Assessment of Cloud - based Health Monitoring using Homomorphic Encryption. In: Computer Design (ICCD), 2013 IEEE 31st International Conference on DOI: 10.1109/ICCD.2013.6657078 Publication Year: 2013 , Page(s): 443 - 446 .
pdfAlbert Feeny, Lichy Han, Larisa G. Tereshchenko, Repolarization lability measured on 10-second ECG by spatial TT′ angle: Reproducibility and agreement with QT variability. J Electrocardiol. 2014 Jun 9. pii: S0022-0736(14)00168-X. doi: 10.1016/j.jelectrocard.2014.06.003.
pdfMassimo W. Rivolta, Luca T. Mainardi, Roberto Sassi, Quantification of Ventricular Repolarization Heterogeneity during Moxifloxacin Administration using V-index Cardiovascular Oscillations (ESGCO), 2014 8th Conference of the European Study Group on, vol.,no.,pp.183,184,25-28 May 2014 doi: 10.1109/ESGCO.2014.6847580
pdfRobert L. Lux, Christopher Todd Sower, Nancy Allen, Susan P. Etheridge, Martin Tristani-Firouzi1, Elizabeth V. Saarel2. The Application of Root Mean Square Electrocardiography (RMS ECG) for the Detection of Acquired and Congenital Long QT Syndrome PLoS ONE 9(1): e85689. doi:10.1371/journal.pone.0085689

 

2013 - Manuscripts

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2013
6 publications
pdfY Zhu, X Yang, Z Wang, Y Peng. Comparative Analysis of Short-Term Vari ability of RR and QT Intervals for the Assessment of Autonomic Nerve Activity ISSN 2325-8861 Computing in Cardiology 2013; 40:73-76
pdfJ Halamek, P Jurak, P Leinveber, V Vondra, JP Couderc. Comparing the Relationsh ip between QT/RR Slope and Basal QTc in LQT1 Patients and Healthy Subjects ISSN 2325-8861 Computing in Cardiology 2013; 40:65-68
pdfM Llamedo, JP Martínez, M Albertal, D Romero,E Pueyo, P Laguna. Morphologic Features of the ECG for Detection of Stress-Induced Ischemia ISSN 2325-886 Computing in Cardiology 2013; 40:591-594
pdfN Scarcelli, M Couderc, MN Baco, J Egah, Y Vigouroux. Clonal diversity and estimation of relative clone age: application to agrobiodiversity of yam (Dioscorea rotundata) Scarcelli et al. BMC Plant Biology 2013,13:178 http://www.biomedcentral.com/1471-2229/13/178
pdfGoodsaid F, Mates WB. The path from Biomarker Discovery to Regulatory Qualification. Academic Press; 1 edition (August 15, 2013), ISBN- 10: 0123914965, 208 pp
pdfSur S, Han L, Tereshchenko LG. Comparison of Sum Absolute QRST Integral, and Temporal Variability in Depolarization and Repolarization, Measured by Dynamic Vectorcardiography Approach, in Healthy Men and Women. PLoS One 2013;8(2):e57175

 

2012 - Manuscripts

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2012
9 publications
pdfGuldenring D. et al. Estimation performance of a reduced lead system during continuous 12-lead ECG ST-segment monitoring. J Electocardiol., 2012,604-608
pdfHasan MA, Abbott D, Baumert M.Beat-to-Beat Vectorcardiographic Analysis of Ventricular Depolarization and Repolarization in Myocardial Infarction.PLoS One. 2012;7(11):e49489. doi: 10.1371/journal.pone.0049489.
pdfRoberto Sassi, Luca T Mainardi. Quantification of Spatial Repolarization Heterogeneity: Testing the Robustness of a New Technique.Computing in Cardiology 2012; 39:69-72.
pdfHalamek J, Couderc JP, Jurak P, Vondra V, Zareba W, Viscor I, Leinveber M Sc P. Measure of the QT-RR Dynamic Coupling in Patients with the Long QT Syndrome.Ann Noninvasive Electrocardiol. 2012 Oct;17(4):323-30.
pdfPickham D, Mortara D, Drew BJ. Time dependent history improves QT interval estimation in atrial fibrillation.J Electrocardiol. 2012 Nov.,45(6):556-60.
pdfTereshchenko LG, Cygankiewicz I, McNitt S, Vazquez R, Bayes-Genis A, Han L, Sur S, Couderc JP, Berger RD, Bayes de Luna A, Zareba W.Predictive Value of Beat-to-Beat QT Variability Index across the Continuum of Left Ventricular Dysfunction: Competing Risks of Non-cardiac or Cardiovascular Death, and Sudden or Non-Sudden Cardiac Death. Circ Arrhythm Electrophysiol. 2012. doi:10.1161
pdfMathias Baumert, Vito Starc, Alberto Porta. Conventional QT Variability Measurement vs. Template Matching Techniques: Comparison of Performance Using Simulated and Real ECG. : PLoS ONE 2012, 7,7:e41920
pdfCouderc JP,Xia X,Denjoy I,Extramiana F,Maison-Blanche P, Moss AJ, Zareba W, Lopes CM: Genotype- and Sex-Specific QT-RR Relationship in the Type- 1 Long-QT Syndrome. J Am Heart Assoc. 2012;doi: 10.1161
pdfLaura Burattini and Roberto Burattini.Characterization of Repolarization Alternansin the Coronary Artery Disease. Department of Information Engineering,Polytechnic University of Marche, Ancona,Italy

 

2011 - Manuscripts

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2011
3 publications
pdfSassi R, Mainardi L. An estimate of the dispersion of repolarization times based on a biophysical model of the ECG. IEEE 2011.IEEE Trans Biomed Eng. 2011 Dec;58(12):3396-405.
pdfDarpo B, Fossa AA, Couderc JP, Zhou M, Schreyer A, Ticktin M, Zapesochny A.Improving the precision of QT measurements.Cardiol J. 2011;18(4):401- 10.
pdfAbrahamsson C, Dota C, Skallefell B, et al. DeltaT50-a new method to assess temporal ventricular repolarization variability. J Electrocardiol 2011;44:477-479.

 

2010 - Manuscripts

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2010
17 publications
pdfJing Wu,Xiaojuan Xia,Jean-Philippe Couderc,Modified ∏-shaped Finite Impulse Response Filter for Stabilization of QT Measurement.Computing in Cardiology 2010;37:489-492
pdfJohannesen L, Grove USL, Sørensen JS, Schmidt ML, Couderc JP, Graff C. A Wavelet-Based Algorithm for Delineation and Classification of Wave Patterns in Continuous Holter ECG Recordings. Computing in Cardiology 2010;37:979−982
pdfSørensen JS, Johannesen L, Grove USL, Lundhus K, Couderc JP, Graff C. A Comparison of IIR and Wavelet Filtering for Noise Reduction of the ECG. Computing in Cardiology 2010;37:489−492
pdfJohannesen L, Grove USL, Sørensen JS, Schmidt ML, Graff C, Couderc JP. Analysis of T-wave Amplitude Adaptation to Heart Rate Using RR-binning of Long-Term ECG Recordings. Computing in Cardiology 2010;37:369−37
pdfHalámek J, Jurák P, Lipoldová J, Leinveber P. QT/RR Coupling and Gender Difference. Computing in Cardiology 2010;37:365?368
pdfBaas T, Gravenhorst F, Fischer R, Khawaja A, Dössel O. Comparison of three T-Wave Delineation Algorithms based on Wavelet Filterbank, Correlation and PCA. Computing in Cardiology 2010;37:361−36
pdfCouderc JP, Xia J, Xu X, Kääb S, Hinteeser M, Zareba W. Static and Dynamic Electrocardiographic Patterns Preceding Torsades de Pointes in the Acquired and Congenital Long QT Syndrome. Computing in Cardiology 2010;37:357−360
pdfJie X, Rodriguez B, Pueyo E. Torsadogenic Drug-induced Increased Short-term Variability of JT-area. Computing in Cardiology 2010;37:353−356
pdfKhawaja A, Petrovic R, Safer A, Baas T, Dössel O, Fischer R. Analyzing Thorough QT Study 1 & 2 in the Telemetric and Holter ECG Warehouse (THEW) using Hannover ECG System HESR: a Validation Study. Computing in Cardiology 2010;37:349−352
pdfJ.P. Couderc . A scientific repository to support the research and development of technologies related to quantitative electrocardiography: the Telemetric and Holter ECG Warehouse (THEW). Cardiol J 2010;17(4):416-9
pdfBurattini L, Zareba W, Burattini R. Identification of gender-related normality regions for T-wave alternans. Ann Noninvasive Electrocardiol 2010 October;15(4):328-36
pdfX. Jie, B. Rodriguez, and E. Pueyo, "A new ECG biomarker for drug toxicity : a combined signal processing and computational modeling study," in Conf.Proc.IEEE Eng Med.Biol.Soc., 978-1-4244-4124 ed 2010, pp. 2565-2568
pdfJ. P. Couderc, "The Telemetric and Holter ECG Warehouse Initiative (THEW): a Data Repository for the Design, Implementation and Validation of ECG-related Technologies," in Conf.Proc.IEEE Eng Med.Biol.Soc., 978-1-4244-4124 ed 2010, pp. 6252-6255
pdfJ. P. Couderc and C. M. Lopes, "Short and long QT syndromes: does QT length really matter?," J Electrocardiol., vol. 43, no. 5, pp. 396-399, Sept.2010
pdfB. J. Drew, "Response to the authors: Dr. Nieminen and Dr. Verrier," J Am Coll Cardiol, vol. 56, no. 3, pp. 241-242, July2010
pdfJ.P. Couderc . A unique digital electrocardiographic repository for the development of quantitative electrocardiography and cardiac safety: the Telemetric and Holter ECG Warehouse (THEW). J Electrocardiol 2010 November;43(6):595-600
pdfJ. Halamek, P. Leinveber, V. Vondra, and J. Lipoldova, "Gender dependency of the QT parameters,". N. Wessel, Ed. 2010, pp. 1-4

 

2009 - Manuscripts

Click on the PDF icon to download the corresponding manuscript:

2009
2 publications
pdfJ. P. Couderc, "Measurement and regulation of cardiac ventricular repolarization: from the QT interval to repolarization morphology," Philos. Transact. A Math. Phys. Eng Sci., vol. 367, no. 1892, pp. 1283-1299, Apr.2009.
pdfJ. P. Couderc and W. Zareba, \"An update on QT measurement and interpretation methodologies,\" Ann. Noninvasive. Electrocardiol., vol. 14 Suppl 1, p. S1-S2, Jan.2009