Cardiac Patients with Atrial Fibrillation

IDENTIFICATION : E-OTH-12-0073-011

This database includes 12-lead continuous recordings (from 73 ECGs from patients with persistent AF referred for cardioversion). The patients were followed for 4 weeks after cardioversion. Patients were offered ECG if they suffered from symptoms of arrhythmia recurrence at any time during the study. All patients underwent a final ECG evaluation at four weeks post-cardioversion.

afib

Example of tracings (II, aVR, and V3) from patient 1098 from E-OTH-12-73-011

Study Design: Patients were considered asymptomatic if AF was diagnosed on routine ECG without any concomitant symptoms. Arrhythmia duration was defined as the time elapsed from symptom onset (or in case of asymptomatic AF, from the last documented SR) until cardioversion. All patients underwent external DC-cardioversion. Cardioversion was considered successful if AF was abolished followed by at least two sinus beats.

IMPORTANT: All patients successfully cardioverted underwent a 12-lead ECG prior to hospital discharge. The post-discharge ECG tracings are NOT INCLUDED in the database.

All patients were followed for four weeks. Cardioactive drugs were left unchanged for the duration of the study. The exclusion criteria for the study were pharmacological treatment with Class I or III anti-arrhythmic drugs, planned changes in pharmacological regime, overt congestive heart failure or ischaemic heart disease, or implanted pacemaker. All patients gave written informed consent. The study was approved by the local Ethics Committee of the enrolling organization and complied with the Declaration of Helsinki. The patients were rested supine for 10-20 min in a quiet room. The 12-lead ECGs were acquired prior to cardioversion.

Number of Leads: 12 lead standard configuration

Sampling Frequency : 1000Hz

Amplitude Resolution: 0.6 microVolt (16 bit)

File Naming Convention: Each filename is composed by "ID" which identifies the patients id and the letter "a".

Clinical Information: A limited list of clinical information available for these patients are described in the following table. The complete list of clinical information includes in addition: history of Afib, presence of coronary artery disease, presence of myocardial infarction, history of hypertension, ejection fraction, hypokalemia, etc...

  Unsuccessful Afib conversion* Successful Afib conversion*
N
41
32
Gender
11 females
11 females
Age (yrs)
68+/-12
68+/-8
AFib duration (days)
162+/-182
130+/-121

* based on a four weeks follow-up after cardioversion.

Clinical Information:

ID ID = 'Study Identifier'
ECG  
Date of cardioversion Date of atrial fibirllation cardioversion
Date of the second ECG Date of the second ECG
Rhythm at follow-up (AF=0,SR=1) Rhythm at follow-up (Atrial Fibrillation =0,Sinus Rhythm=1)
Follow-up (days) Follow-up (days)
Male / Female (1/0) Male / Female (1/0)
Age (yrs) Age (yrs)
Co-morbidity  
hypertension hypertension
Vavular disease Vavular disease
Ischemic heart disease Ischemic heart disease
Acute Myocardial infarction Acute Myocardial infarction
1.PCI 2.CABG 3.Both 1.Percutaneous coronary intervention 2.coronary artery bypass graft surgery 3.Both
Date of most recent Date of most recent
congestive heart failure congestive heart failure
Diabetes Mellitus Diabetes Mellitus
Any comorbidity Any comorbidity
Lone AF Lone AF
Previous AF episodes Previous AF episodes
Afib onset and duration  
AF onset (unclear=0) AF onset (unclear=0)
Last documented sinus rhythm Last documented sinus rhythm
First Documented Afib First Documented Afib
Detection (symptome:1, ECG:2, CHF:3) Detection (symptome:1, ECG:2, Cardiac Heart Failure:3)
Afib duration (days) Afib duration (days)
Medication  
Digitalis Digitalis
Betablockers Betablockers
Calcium inhibitor Calcium inhibitor
sotalol sotalol
Class 1c Class Ic
Class III Class III
ACEi/A2 ACEi/A2
Spironolactone Spironolactone
No heart active drug (yes:1) No heart active drug (yes:1)
Warfarin Warfarin
Ultrasound cardiography  
Date Date
Left artery diameter (mm) Left artery diameter (mm)
Ejection Fraction (0=norm, 1=mild, 2=moderate, 3=severe) Ejection Fraction (0=norm, 1=mild, 2=moderate, 3=severe)
Ejection fraction (%) Ejection fraction (%)

 

 

Related Publications:

(1) Holmqvist F, Stridh M, Waktare JE, Sornmo L, Olsson SB, Meurling CJ. Atrial fibrillatory rate and sinus rhythm maintenance in patients undergoing cardioversion of persistent atrial fibrillation. Eur Heart J 2006; 27(18):2201-2207.

(2) Holmqvist F, Stridh M, Waktare JE, Roijer A, Sornmo L, Platonov PG et al. Atrial fibrillation signal organization predicts sinus rhythm maintenance in patients undergoing cardioversion of atrial fibrillation. Europace 2006; 8(8):559-565.